Abstract

EVALUATION OF THE ASSOCIATION OF FOOD OF ANIMAL ORIGIN WITH DIAZINON LEVELS IN AMNIOTIC FLUID

Al-Batol Essa*, Ekbal Fadel, Flora Mayhoub and Hasan Saleh

ABSTRACT

The study continued for a full year, from May 2022 to 2023, at Tishreen University Hospital in Latakia Governorate, and 190 triplicate samples (father, mother, and newborn) participated. This study aimed to clarify the source of dietary exposure of animal origin in the pregnant mother, and to evaluate the exposure of the human fetus to diazinon residues. Then the relationship between food of animal origin in the pregnant mother and diazinon levels in the amniotic fluid was studied. Consent was obtained from the father and mother to conduct the questionnaire, which included consent to take an amniotic fluid sample. A high-performance liquid chromatograph was used to assay organophosphorus pesticide residues in amniotic fluid. To find relationships between potential sources of exposure inpregnant mothers and diazinon residue concentrations in amniotic fluid, we used SPSS Statistics 23.0 (Statistical Package for the Social Sciences). The concentrations of diazinon residues varied between the samples studied, ranging between (0.02 ppb) and (5.72 ppb). High consumption of meat and broilers was associated with lower levels of diazinon used in feedlots, and we observed no other significant relationship between amniotic fluid diazinon concentrations and general neonatal characteristics, which indicates that the measured concentrations do not pose a risk to the fetus.

Keywords: Human fetus, amniotic fluid, diazinon, meat, chicken, Syria.