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INVIVO SCREENING FOR THE SKELETAL MUSCLE RELAXANT PROPERTY BY THE LEAF EXTRACT OF SARACA ASOCA
Syeda Qadar Unnisa*, Babera Naaz, Ashreen Unnisa, Tasleem Fatima, Meraj Sultana and Juveria Afreen
ABSTRACT
Background: Saraca asoca (Fabaceae), a highly valued medicinal tree in Ayurvedic medicine, has been traditionally used as a 'universal panacea'.[1] This study aimed to evaluate the skeletal muscle relaxant properties of the plant's leaf extract. Materials and Methods: The dried plant powder was processed via Soxhlet extraction using ethanol as a solvent. The muscle relaxant activity was assessed in Male Wistar rats using in vivo methods, including the rotarod test, chimney test, and grip strength test. These tests measured the performance reduction in animals before treatment and at 30 and 60 minutes post-administration of the standard drug and ethanolic extract. Results: The results indicated a significant muscle relaxation effect, with the highest response observed at 60 minutes. Among the treatment groups, the ethanolic extract at 400 mg/kg produced a more pronounced skeletal Keywords: Saraca asoca, Ayurvedic, Soxhlet, Rotarod, Wistar Rats, EESA. [Download Article] [Download Certifiate] |