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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

AN ANALYTICAL METHOD FOR THE ESTIMATION OF THIOCOLCHICOSIDE AND ACECLOFENAC IN PHARMACEUTICAL DOSAGE FORMS

Pradeep Kumar*

ABSTRACT

A new RP- HPLC method was developed and validated for the estimation of aceclofenac and thiocolchicoside in their tablet dosage form. The chromatographic separation was carried out by using Agilent Zorbax column (150 × 4.6mm, 5μm). The mobile phase containing the combination of methanol & 0.1% ortho phosphoric acid in the 75: 25 (v/v) ratios. In this method the ow rate used is 1 min/ml for the separation at the detection wavelength of 275 nm. The proposed method was validated according to the ICH guidelines. The method was linear (R2 >0.99), precise (RSD < 2.0%), accurate, simple, sensitive and robust. This method can be successfully used for the routinepharmaceutical analysis.

Keywords: Thiocolchicoside; Aceclofenac; RP- HPLC; Method development; Validation.

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