Abstract

ASSESSMENT OF RED BLOOD CELL DISTRIBUTION WIDTH, SERUM TRANSFERRIN RECEPTOR, AND SERUM TRANSFERRIN RECEPTOR INDEX IN IRON DEFICIENCY ANEMIA OF PREGNANCY

BaybeenK. AL-Selevany /PhD, Hana Abdul -Qaderkhuder

ABSTRACT

Background: Iron deficiency anemiais a medical and public health problem. Pregnant women constitute a high risk group for Iron deficiency. Maternal iron deficiency and particularly Iron deficiency anemia may be associated with detrimental effects on maternal and infant function and particularly with a higher risk of preterm delivery and delivery of low birth weight neonates. Objectives: to evaluate the role of RDW,sTfR and sTfRI in pregnant women suffering from IDA. Materials And Methods: The study group conducted on 180 pregnant women of childbearing age (18-43) yearsattending the obstetrics and gynecology unit of Al-Khansa'a Teaching Hospital and AL-BatoolTeaching Hospital in Mosul city. Out of these,90 werepregnant patients withIron deficiency anemiaand 90 were healthy normal pregnancy consideredas controls. In the current study three recent tests such as RDW,sTfR and sTfRI were added to routine measurements to diagnosis IDA clinically in pregnantwomen. Results: the resultsindicate thatpregnant patients with IDA exhibited significant decrease in HbL, PCV, MCV, MCH, MCHC and increase RDW in P-IDAas compared with healthy pregnant control.SFL was significant lower; whilesTfR andsTfRIwere significantly higher inP-IDA compared to control. Furthermore there was a significant negative correlation between and RDW and MCV and P-IDA.A significant positive correlation is found between sTfR and sTfRIin P-IDA Conclusions: In general the results of this study revealed that RDW, sTfR and sTfRImight provide additional and useful laboratory tests for the assessment of anemia caused by IDA.

Keywords: RDW, sTfR, sTfRI,IDA of Pregnancy