Abstract

NANOROBOTS: AN INNOVATIVE APPROACH FOR DNA-BASED CANCER TREATMENT

Rashmi Ravindra Patil*, Raj Gulab Patil, Ravindra Vishwasrao Patil and Prof. Swati R. Borse

ABSTRACT

When it comes to cancer therapy, nanorobots are at the forefront of innovation because they allow for precision targeting and direct delivery of therapeutic payloads to tumor locations. By utilizing the latest developments in DNA nanotechnology, these tiny instruments have the potential to completely transform cancer treatment because of their capacity to precisely target malignant cells while navigating the complex anatomy of the human body. In order to better understand the potential of DNA-based nanorobots for cancer therapy, this study examines their functioning, design, and therapeutic uses. In particular, we talk about building programmable nanorobots with targeted medicine delivery and disease biomarker detection using DNA origami as a platform. Through the exploitation of DNA's special qualities, nanorobots may be designed to elude the immune system, get past
biological barriers, and react quickly to the surroundings of tumors. DNA-based nanorobots provide a promising way to maximize therapeutic efficacy while reducing side effects on healthy tissues through fine control and customisation. The research and use of nanorobot technology, however, still faces several obstacles, such as safety worries, scaling problems, and legal restrictions. Interdisciplinary cooperation as well as ongoing innovation in the fields of biotechnology, clinical research, and nanoscience are necessary to meet these difficulties. Nanorobots have the potential to significantly transform cancer therapy despite these challenges by providing new pathways for individualized, focused, and minimally invasive therapies. The transformational potential of DNA-based nanorobots for cancer therapy is highlighted in this abstract, along with the significance of further research efforts to realize these robots' full potential in clinical settings.

Keywords: Nanorobots, Cancer treatment, Targeted delivery, Precision medicine, Biomarker targeting, Responsive nanotechnology, Drug delivery, Biocompatibility.