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Abstract

DEVELOPMENT AND VALIDATION OF SIMPLE HPLC METHOD FOR ESTIMATION OF TERBINAFINE HYDROCHLORIDE IN BULK AND IN-HOUSE FORMULATED MICROEMULSION

Sayali V. Ganjiwale*, A. P. Dewani and A. V. Chandewar

ABSTRACT

In the present work HPLC method has been developed for the quantitative estimation of terbinafine hydrochloride in bulk drug and pharmaceutical formulations. A rapid and sensitive HPLC method with PDA detection (249nm) for routine analysis of in bulk drug and pharmaceutical formulation development and Application of HPLC method for analysis of terbinafine microemulsion formulation.

Keywords: Reverse phase high pressure liquid chromatography (RP-HPLC); Terbinafine Hydrochloride; International Conference on Harmonisation (ICH); Photodiode array (PDA) detection.


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