Abstract

A COMPREHENSIVE REVIEW ON: PEPTIC ULCERS

A. M. Krupanidhi*, Prakash Dabadi and Mujeebulla R. H.

ABSTRACT

Peptic ulcers are a common illness that occurs in the stomach, duodenum, and oesophagus. They are caused by a combination of factors that contribute to the erosion of the mucosal lining of the stomach. The pathophysiology of peptic ulcer disease is still unknown, and the exact aetiology of this illness is still unclear. The most common signs and symptoms of stomach ulcers include abdominal pain, bloating, heartburn, and gastritis. Several in vivo models have been developed to study the pathogenesis, prevention, and treatment of gastric ulcers. These models are valuable for investigating host-pathogen interactions and evaluating anti-H. pylori therapies. In vitro screening models are utilized for studying the occurrence and progression of a variety of ulcers, as well as evaluating potential treatments.

Keywords: Peptic ulcer, NSAID, Indomethacin, Pantoprazole.