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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

IN VIVO ANTIOXIDANT AND ANTIHYPERGLYCAEMIC PROPERTIES OF AQUEOUS EXTRACT OF A HERBAL COCKTAIL

¹Ogugua V N, ²Egba S I٭, and ¹Adoga J E.

¹Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria.

²Department of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.

ABSTRACT

The antioxidant and antihyperglycaemic effect of herbal cocktail namely: vernonia amygdalina, Gongronema latifolium, Allium sativium, Ocimum gratissmun and Aloe barbadensis was studied on alloxan induced Diabetic Rat. Twenty (20) albino wistar Rats were equally divided into five groups. Groups 1 and 2 served as normal and untreated Diabetic controls. Test groups 3, 4 and 5 were treated with 10mg/kg glibenclamide, 200mg and 400mg/kg of extract for 28 days. The result showed a dose dependant significant increase (P

Keywords: Antioxidant, catalase, glutathione, alloxan, antihyperglycaemia, glibenclamide.

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