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A NOVEL ZERO ORDER DERIVATIVE SPECTROPHOTOMETRIC METHOD FOR THE VALIDATION AND QUANTIFICATION OF FESOTERODINE FUMARATE
Ch. Sakhinamma*, Y. Prapurnachandra, T. Anuhya, P. Harshitha, N. Hemalatha, M. Deeksha and E. Dharmik Chandu
ABSTRACT
Fesoterodine Fumarate is a competitive muscarinic receptor antagonist that has muscle relaxing and urinary antispasmodic properties. A simple, sensitive, accurate, and reproducible Zero derivative UV spectrophotometric method was developed to determine Fesoterodine in bulk and pharmaceutical dosage forms. The solvent used was distilled water, and the wavelength corresponding to the drug's maximum absorbance was found to be 210 nm, with a correlation coefficient of 0.9995. The method was validated for several parameters, including linearity, accuracy, precision, and robustness, in accordance with ICH guidelines. Keywords: Fesoterodine, Spectroscopy, Absorbance and Wavelength. [Download Article] [Download Certifiate] |