Abstract

MEFENAMIC ACID: AN EMULGELS FOR TOPICAL DRUG DELIVERY SYSTEM

Sangeeta Badatya* and Satyawan Dangi

ABSTRACT

Topical drug delivery is the delivery of drugs anywhere in the body via skin, vaginal, ophthalmic and rectal routes. Pills may be given for localized or systemic results. Topical formulations with varying physicochemical homes, which includes solid, semisolid, or liquid, may be developed. The topical system is created by means of preparing a drug emulsion and incorporating it into an emulgel. Emulgels is a thermodynamically strong method with low interfacial anxiety that is made through combining a surfactant and a co-surfactant and has numerous properties which include multiplied permeability and accurate thermodynamic stability. Emulgel has a twin control and a sustained release pattern. Emulgel improves bioavailability in addition to affected person compliance. The pH, viscosity, particle size, zeta capacity, drug content material, stability study, pores and skin inflammation test, and other properties of the organized formula are evaluated.

Keywords: Topical drug delivery, Emulgel, surfactant, bioavailability.