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CLINICAL PHARMACOLOGY OF IBUPROFEN
Prof. Gian Maria Pacifici
ABSTRACT
Ibuprofen is the anti-inflammatory most used in the United States and is a non-selective cyclooxygenase inhibitor approved for use in treatment of symptomatic rheumatoid arthritis, juvenile arthritis, osteoarthritis, pain, ankylosing spondylitis, acute gouty, tendinitis, bursitis, headache, postoperative dental pain, swelling, and primary dysmenorrhoea. Ibuprofen is supplied in tablets, chewable tablets, capsules, geladas, oral drops, and oral suspension. An injectable formulation of ibuprofen is approved to close the patent ductus arteriosus. Ibuprofen is rapidly absorbed following oral administration and has been found efficacy and safe. The prophylaxis and the treatment with ibuprofen and the trials conducted with ibuprofen have Keywords: efficacy-safely, human tissues, ibuprofen, metabolism, pharmacokinetics, prophylaxis, toxicity, and treatment. [Download Article] [Download Certifiate] |