Abstract

FORMULATION DEVELOPMENT AND CHARACTERIZATION OF ANTI-BACTERIAL CURCUMIN CREAM FOR DENTAL CARIES

Priyanka Singh Patel* and Aman Kumar

ABSTRACT

Different dental diseases can be treated using various methods, but traditional drug therapies often come with numerous side effects. This has sparked interest in exploring natural compounds from plants for better dental treatments. Plants have long been used for medicinal purposes, with curcumin being recognized for its medicinal properties in traditional medicine. This study aims to leverage curcumin's effectiveness in maintaining oral health and managing dental issues like dental caries. To achieve this, a curcumin-based dental cream was developed specifically for treating dental caries. The cream was formulated using homogenization techniques for emulsion preparation. Before formulation, pre-formulation studies such as physical, UV, and NMR characterizations were conducted. The formulated dental cream underwent various tests including particle size analysis, polydispersity index, zeta potential analysis, drug content analysis, stability studies, and in-vitro antibacterial evaluation. The findings suggest that curcumin-based dental cream offers a promising alternative to synthetic creams, though further stability studies are necessary to enhance product quality.

Keywords: Curcumin, Antibacterial, In-vitro Antimicrobial, Curcuma longa, Dental caries, Dental cream.