Abstract

ISOLATION OF NIMBOLIDE FROM AZADIRACHTA INDICA LEAF EXTRACT AND ITS ANTIOXIDANT, ANTIBACTERIAL AND ANTI-DIABETIC PROPERTIES

R. Vijayan*, T. Sathya, M. Reshmi, V. Sowntharya and R. Kokilavani

ABSTRACT

A. indica often known as neem, or Indian Lilac which belongs to mahogany family in Meliaceae. It has been found that the neem is native to Asian countries. Neem is known for its pharmacological activities such as anti-inflammatory, anti-microbial, anti-diabetic and anti-oxidant properties. Our project starts with the collection of neem leaves and Extraction of the neem leaves extract, to check the phytochemical Analysis of Neem extract. Then to isolate the Nimbolide compound from Neem by using Chromatography Technique. Isolated compound was tested for its Antimicrobial activity against the infective pathogens. Antioxidant assay activity as well as Antidiabetic parameters were carried out and the results aresummarised.

Keywords: Neem is known for its pharmacological activities such as anti-inflammatory, anti-microbial, anti-diabetic and anti-oxidant properties.