Abstract

REGULATION OF LIPID METABOLISM BY HORMONES

Dornala Chaitanya Dixit*, M. Pharm and Shaik Abdulla

ABSTRACT

There is a wide variety of kinds of lipids, and complex structures which determine thediversity and complexity of their functions. With the basic characteristic of water insolubility, lipid molecules are independent of the genetic information composed by genes to proteins, which determine the particularity of lipidsint hehumanbody, with wateras thebasic environment and genes to proteins as the genetic system. In this review, we have summarize edthecurren tlandsca peonhor moneregul ationofli pidmet abolism. Afterthewell-studiedPI3K-KTpathway, insulin ffectsfatsy nthesisb ycontro llingth eactivit yandprodu ctionofv arioustran scription factors. New mechanisms of thyroid hormone regulation are discussed, receptorαand β may mediate different procedures, the effect of thyroid hormone on mitoch ondria provides a new insight for hormones regulating lipid metabolism. Physiological conce ntrationo fadrenal ineindu cestheex pressi onofextrapi tuitarypr olactinina diposetissue macrophages, which promotes fat weight loss. Manipulation of hormonal action has the potential to offer anewth erapeutic horizonfort hegloba lburden ofobesity and itsassoc iatedcom plicatio nssuchas morbid itya ndmortality.

Keywords: In this review, we have summarize edthecurren tlandsca peonhor moneregul ationofli pidmet abolism.