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FORMULATION, DEVELOPMENT AND EVALUATION OF ALOE VERA EXTRACT CAPSULES DELIVERY SYSTEM AS AN ADVANCED PHYTOTHERAPY APPROACH FOR CONTROLLING DIABETES
Prof. Dr. Mahmoud Mahyoob Alburyhi* and Prof. Dr. Amina El-Shaibany
ABSTRACT
Diabetes is a serious health concern in many countries with high blood glucose, obesity, and multiple organ failures in late stages. Treating diabetes with effective drugs is still a challenging issue since most of the available diabetic drugs are not effective in combating diabetes, especially in secondary disease complications like obesity retinopathy, and nephropathy associated diabetes. Hence search for effective anti-diabetic medication, especially from natural sources is mandatory with no adverse side effects. The Aloe Vera plant widely distributed in Yemen. It is used internally to counter most of the problems of digestion, diabetes, immune system, and peptic ulcers. It also contains antibacterial, antiseptic, antiviral, anti-inflammatory, anti-tumor, anti-oxidant, moisturizing and anti-aging effects. hence widely used for the treatment of cancer. The flower of Aloe Vera were collected from Saada, Yemen, and was prepared by encapsulation of powders from the Aloe Vera flower extract with various concentration of excipients. In the present study the Aloe Vera was formulated as capsules and evaluate for organoleptic properties using tests as, weight variation, drug content, in-vitro dissolution and other evaluation parameters. It Keywords: Aloe Vera, Extract, Capsules, Medicinal herbs, Antidiabetic, Phytotherapy. [Download Article] [Download Certifiate] |