![]() |
|||||||||||||
|
All | Since 2019 | |
Citation | 5450 | 3969 |
h-index | 23 | 20 |
i10-index | 134 | 84 |
ADVANCES IN RECENT PELLETIZATION TECHNIQUES FOR CONTROLLED DRUG DELIVERY IN PHARMACEUTICALS
Kalyani S.*, Sakshi P., Vedant B., Shubham S., Sonali P. and Leena C.
ABSTRACT
Pellets, those tiny spherical particles measuring between 0.5mm to 1.5mm, have quietly revolutionized the world of pharmaceuticals. Think of them as small, round heroes, designed primarily for oral medication. These unassuming spheres, when packed with drugs, offer numerous advantages over traditional single-unit doses like tablets or capsules. Imagine this: when you take multiple-unit pellets, they journey through your gastrointestinal tract, behaving differently than their single-unit counterparts. They're less dependent on when your stomach empties, smoothly passing through the pyloric sphincter. This reduces the variability in how long they stay inside you, which is a big win for drug effectiveness. Pellets can take on different forms, such as being packed into hard gelatin capsules or even compressed into Keywords: Pelletization, Pellets, Extrusion-spheronization, Bioavailability, Cryopelletization. [Download Article] [Download Certifiate] |