Abstract

TRANSDERMAL ROUTE AND DRUG DELIVERY BY SKIN

Bhambare Arti Kailas*, Ekhande Ashvini Keru and Mhaske P. B.

ABSTRACT

Transdermal drug delivery systems (TDDS) are the dosage form of adhesive patch that is placed on the skin to deliver specific dose of medication through the skin and in to the blood stream. Transdermal drug delivery system (TDDS) are topically administered medicaments in the form of patches that deliver drugs for systemic effects at a predetermined and controlled rate. It works very simply in which drug is applied inside the patch and it is worn on skin for long period of time. This transdermal route of drug delivery has more benefits and convenience than oral route and enhances the safety and efficacy of drug; it is patient friendly and painless device that provides regulated, uniform administration and the continuous supply of drug to targeted site for treatment of various diseases. The TDDS review article provides variable information regarding TDDS and its evaluation process details as a ready reference for a research scientist who is involved in TDDS.

Keywords: TDDS, Microneedles, permeation enhancers, Diffusion.