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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

LIPID PEROXIDATION, ANTIOXIDANTS AND HAEMATOLOGICAL CHANGES IN ALLOXAN-INDUCED DIABETIC RATS EXPOSED TO GENERATOR EXHAUST FUMES

¹Ogugua V N٭, ²Egba S I, and ¹Omaliko G I

¹Department of Biochemistry, University of Nigeria, Nsukka, Enugu State, Nigeria.

²Department of Biochemistry, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.

ABSTRACT

The possible effect of exposure to generator exhaust fumes on lipid peroxidation and some haematological indices in alloxan induced diabetic rats were studied. Test groups consist of normal rats exposed to fumes, diabetic rats exposed to fumes and diabetic rats not exposed to fumes. Normal rats served as normal control and were not exposed to fumes. The result of the study showed a significant increase in the level of Met-haemoglobin, Total white blood cell count and haemoglobin concentration in diabetic rats exposed to fumes compared to other test groups and the control. A significant increase (P

Keywords: Haematological, Lipid peroxidation, Alloxan, Methaemoglobin, Catalase, Glutathione.

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