Abstract

ESR IN RHEUMATOID ARTHRITIS—A REVIEW

Fasih Ahmad*, Mohammad Naime, Arifa Khatoon, Mahboobus Salam, Ehsan Rauf, Mohd. Nafees Khan

ABSTRACT

Rheumatoid Arthritis (RA) is a chronic autoimmune disorder characterized by inflammation of the synovial joints, leading to joint damage and functional impairment. Erythrocyte Sedimentation Rate (ESR) has long been recognized as a valuable biomarker in the diagnosis and management of RA. This comprehensive review explores the role of ESR as an indicator of systemic inflammation in RA. The ESR test measures the rate at which red blood cells settle in a tube, reflecting the presence of inflammatory proteins in the blood. Numerous studies have shown a correlation between elevated ESR levels and the severity of RA, making it a useful tool for assessing disease activity. Moreover, longitudinal monitoring of ESR aids in tracking the progression of inflammation over time and evaluating treatment efficacy. Despite its utility, ESR is a non-specific marker and can be influenced by various factors, including age, sex, and other medical conditions. Clinicians often combine ESR results with other inflammatory markers and clinical assessments to obtain a more accurate picture of disease activity. Advancements in technology have
led to the development of more specific biomarkers in RA diagnosis, yet ESR remains a cost-effective and widely accessible tool in clinical practice. ESR continues to play a crucial role in the management of RA by providing valuable insights into the inflammatory status of patients. As research progresses, a comprehensive understanding of the interplay between ESR and other biomarkers will further enhance its clinical utility, contributing to more effective and personalized treatment strategies for individuals with Rheumatoid Arthritis.

Keywords: ESR, Rheumatoid Arthritis, Inflammation.