Abstract

FORMULATION AND EVALUATION OF HERBAL OINTMENT AS A ANTIMICROBIAL ACTIVITY

Awinash S. Chavan*, Sakshi Ambhore, Pankaj Ahewad, Akshada Badar, Mangesh Bambarde and Gajanan Mogal

ABSTRACT

This study focuses on the formulation and evaluation of an antimicrobial herbal ointment derived from local medicinal plants. Ethanolic extracts from selected plants were combined in different ratios, and antimicrobial tests were conducted to identify the most effective combination against Staphylococcus aureus, Escherichia coli, and Klebsiella species. The ointment formulation incorporated the identified active ingredients in the most effective ratio into a prepared ointment base. The quality of the ointment was assessed based on irritancy, spreadability, diffusion, and stability. The results provide insights into the potential of herbal remedies for formulating effective and safe topical antimicrobial treatments.

Keywords: Staphylococcus aureus, Escherichia coli, Irritancy, Spreadability, Diffusion, Stability.