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Abstract

NEXT GENERATION TOOLS IN M RNA PURIFICATION: THE ROLE OF CONTINOUS RAMAN SPETTROSCOPY TESTING WITH PRETREATEMENT OF THE SAMPLE

*Luisetto M., Nili B. Ahmadabadi, Khaled Edbey, Riccardo Benzi Cipelli and Oleg Yurevich Latyshev

ABSTRACT

In biopharmaceutical productions field the purification proces is a crucial step in order to obtain. Drugs whit impurity profile according the regulatory agency requirement. Aim of this work is to verify some relevant and recent literature and after analysis to submit to the researcher new Solutions in order to improve the global safety and the toxicological profile: is is submitted a project related the in continious testing of the purified materials using Raman spettroscopy – with pre treatement of the sample.

Keywords: M RNA, Purifications, cromatography, separations, columns, resins, monoliths, activated carbon, Raman spettroscopy, pre treatement of sample, continuous testyng systems.


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