Abstract

A REVIEW ON ANALYTICAL METHOD OF CARIPRAZINE AS AN ANTIPSYCHOTIC DRUG

Krutika Patel*, Margi Patel, Khushbu Patel and Dr. C. N. Patel

ABSTRACT

Cariprazine is one of the newest dopamine-serotonin partial agonists, also known as ‘atypical’ second generation antipsychotics. Originally approved for acute and maintenance treatment of schizophrenia as well as for acute mania and mixed mania/depression, cariprazine has now been approved for bipolar I depression. Maintenance studies are in progress in bipolar disorder, as are studies to augment antidepressants in unipolar major depressive episodes insufficiently responsive to treatment. Here, we review specifically the efficacy and safety data of cariprazine in bipolar I disorder and discuss the hypothesized mechanism of action of cariprazine and how it could theoretically be linked to Cariprazine’s broad therapeutic actions across the mood disorder spectrum.

Keywords: Cariprazine, Bipolar depression, Bipolar disorder, Cariprazine, Schizophrenia.