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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

PHYTOCHEMICAL CONSTITUENTS AND BIOACTIVITY OF DIFFERENT PLANTS FROM GULMI DISTRICT OF NEPAL

Bimala Subba* and Rishi Ram Paudel

ABSTRACT

Phytochemical and biological screenings of some medicinal plants like Schima wallichii, Psidium guajava, Bauhinia variegata, Rubia cordifolia and Artocarpus lakoocha of Gulmi district were performed. Potent pharmacological activities were revealed by bark of S. wallichii and leaves of P. guajava. Methanol extracts of bark of S. wallichii and leaves of P. guajava exhibited high toxicity against brine shrimp nauplii at LC50 (μg/ml) values of 31.612 and 25.174 respectively. Similarly, leaves of P. guajava (94.391 mM Fe+2/liter) and bark of S. wallichii (73.669 mM Fe+2/liter) were found to have strong antioxidant power. In addition, S. wallichii leaves, P. guajava and B. variegateexhibited high antibacterial activities against Staphylococcus aureus and Escherichia coli.

Keywords: Methanol extracts, phytochemical screening, biological activities, S. wallichii, P. guajava.

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