Abstract

A REVIEW ON NOVEL DRUG DELIVERY SYSTEM

Sahil Mahajan*, Manjit Kaur and Pooja Kashyap

ABSTRACT

Today there are global movements towards finding of herbal medicaments in plants to bring them in market via a suitable drug delivery system for mankind. The basic thought behind it is treatment of each disease is hidden in nature. However, delivery of herbal drugs also requires modification with the purpose to achieve sustain release, to increase patient compliance etc. previously herbal drugs could not attract scientists towards the modifications of novel drug delivery systems due to processing, standardizing, extracting and identification difficulties. But now days with the advancement in the technology, novel drug delivery systems (NDDS) open the door towards the development of herbal novel drug delivery system. With use ofadvance techniques protection from toxicity, enhancement in stability, improved bioavailability of herbal formulations, protection from physical and chemical degradation can be achieve. Novel drug delivery technologies have gained the importance to achieve modified delivery of herbal drugs their by increasing the therapeutic value as well as reducing toxicity. The present reviews gives information regarding various novel techniques used for improving safety and efficacy of phytomedicines and application of novel formulation. The main goal for developing such delivery systems is to minimize drug degradation and loss, to prevent harmful side effects and to increase bioavailability. Targeting is the ability to direct the drug loaded system to the site of interest. Among drug carrier one can name soluble polymers, microparticles made of insoluble (or) biodegradable natural and synthetic polymers, microcapsules, cells, cell ghosts, lipoproteins, liposomes and micelles. Two major mechanisms can be distinguished for addressing the desired sites for drug release, (a) Passive and (b) Active targeting.

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