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RECENT ADVANCES IN NANO PARTICLE-BASED MICROFLUIDIC TECHNOLOGIES FOR STUDYING TUMOR METABOLISM
Chandan Kumar Raikwar, Nirmalya Dutta, Monalisa Malakar, Anil Kumar, Souvik Kundu, Vishal Pathak, Saiyed Musaratafrin Sabirali, Kruti Bharat Sharma, Ravikumar S. Vaishnov*
ABSTRACT
Microfluidic chip technology emerges as a pivotal tool in biomedical applications, featuring a network of grooves or microchannels etched onto various materials like glass, silicon, or polymers such as polydimethylsiloxane (PDMS) and polymethylmethacrylate (PMMA). These interconnected microchannels within the microfluidic chip, interfaced with the macro- and miniature world through inputs and outputs, provide a mechanism for achieving desired results. In the realm of understanding tumor metabolism, nanoparticle-based microfluidic technologies play a crucial role. These platforms yield distinctive insights into metabolic processes, drug delivery, and interactions within the tumor microenvironment. Recent advancements in nanoparticle design, synthesis, and their integration into microfluidic systems facilitate precise studies of cancer metabolism. The potential impact on cancer research is significant, extending towards personalized therapeutic interventions. This summary underscores the ongoing imperative for exploration and innovation, tackling challenges related to biocompatibility and scalability, and embracing trends like artificial intelligence integration. These collective efforts aim to drive the progression of nanoparticle-based microfluidic technologies, reshaping the landscape of cancer research. The transformative potential of these technologies holds the key to revolutionary advancements in personalized medicine and cancer therapeutics. Keywords: Microfluidic Chip Technology, Nanoparticle, Tumor Metabolism, Biomedical Applications, Personalized Therapeutics, Cancer [Download Article] [Download Certifiate] |