EVALUATION OF ANTI-DIABETIC ACTIVITY OF 2, 4, 6-TRIHYDROXY PHENYL PROPIONATE ISOLATED FROM TRIUMFETTA ROTUNDIFOLIA (LAM). IN STREPTOZOTOCIN INDUCED ON WISTAR RATS
R. Sanilkumar* and A.Kottai Muthu
ABSTRACT
The anti-diabetic activity of 2, 4, 6 - Trihydroxy phenyl propionate isolated from Triumfetta rotundifolia (Lam.) in streptozotocin induced diabetic rats was investigated in the present study. Streptozotocin was used to induce diabetes mellitus. The anti-diabetic potential was assessed by determining oral glucose tolerance, fasting blood glucose, urine glucose, liver glycogen content, serum lipid profile, change in body weight and histopathology studies. 2, 4, 6-Trihydroxy phenyl propionate isolated from Triumfetta rotundifolia was administered to normal and experimental diabetic rats for 15 days. Significant (p
Keywords: Triumfetta rotundifolia, 2, 4, 6-Trihydroxy phenyl propionate, Streptozotocin, Diabetes.
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