Abstract

ANTIBACTERIAL STUDIES WITH METHANOL AND ETHANOL EXTRACTS OF Tagetes patula Flowers AGAINST METHICILLIN-RESISTANT Staphylococcus aureus

Snehali Majumder*, E.M. Elango, J.P.A. Hoebe, Mohammed Rahmatullah

ABSTRACT

The methanolic and ethanolic extract of flowers of Tagetes patula were evaluated for their antibacterial potential against methicillin-sensitive Staphylococcus aureus (MSSA) ATCC 29213 and methicillin-resistant Stphylococcus aureus (MRSA) wild type and ATCC BAA1026 strains. Both extracts demonstrated antibacterial activity against the various strains tested with zone of inhibitions ranging from 18mm to 26mm. The ethanol extract showed better potency against MSSA ATCC 29213, while with both wild-type and ATCC BAA-1026 strains of MRSA, methanolic and ethanolic extracts demonstrated similar potencies with zone of inhibition at 18 mm at the highest concentrations of the extracts tested (50mg/ml). It is concluded that the methanolic and ethanolic extracts of flowers of Tagetes patula may may contain component which are effective against MRSA.

Keywords: Tagetes patula, MRSA, MSSA, flower