![]() |
|||||||||||||
|
All | Since 2019 | |
Citation | 5450 | 3969 |
h-index | 23 | 20 |
i10-index | 134 | 84 |
DESIGN AND DEVELOPMENT OF ORODISPERSIBLE TABLETS OF DOMPERIDONE
*Diganlal Carpenter, Dr. V. P. Gupta and Bhupendra Tiwari
ABSTRACT
The main objective of present work is development of orodispersible tablets of domperidone. Domperidone is dopamine-2 receptor antagonist widely prescribed drug used in the treatment of gastro paresis and any condition causing chronic nausea and vomiting in adults and children. It acts as an antiemetic and a prokinetic agent through its effects on the chemoreceptor trigger zone and motor function of the stomach and small intestine. Thus it provides an excellent safety profile for long-term administration orally in the recommended doses. Domperidone is an effective antiemetic, and improves gastric motility. Keywords: Evaluation, Dosage form, Drug delivery, Diluents, Compactness. [Download Article] [Download Certifiate] |