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DESIGN, SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTI-BACTERIAL SCREENING OF SOME NOVEL 2, 4-DITHIOBIURET BASED PYRIMIDINES
Siddharth A. Waghmare and Swapnil B. Sarkate*
ABSTRACT
The interactions of 2-(3-thiocarbamido) pyrimidines (I-a) and various alkyl/ arylisothiocyanate such as phenylisothiocyanate, ethylisothiocyanate, tertiarybutylisothiocyanate, p tolylisothiocyanate, 4-chlorophenylisothiocyanate (IIa-e) in acetone and ethanol medium have been investigated. The synthesized compounds from these reaction conditions were characterized on the basis of elemental analysis, chemical characteristic and IR, H1-NMR, MASS, spectral data. Keywords: 2-(3-thiocarbamido) Pyrimidines, Substituted alkyl/arylisothiocyanate, acetone, Ethanol, Petroleum ether, Gram Positive and Gram negative bacteria etc. [Download Article] [Download Certifiate] |