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A COMPREHENSIVE REVIEW ON FLOATING DRUG DELVERY SYSTEM
Pradnya D. Lahamge*, Prof. Yashpal M. More, Pallavi P. Ahire, Vinay R. Kothawade
ABSTRACT
The category of gastroretentive drug delivery systems (GRDDS) includes floating drug delivery systems (FDDS). These dose formulations are intended to extend the duration of the stomach's residence period by a sustained release technique. Drugs which are harder to dissolve in high pH environments have improved bioavailability and solubility when incorporated into GRDDS. Reduced intestinal absorption of solid dose forms can be accomplished by the flotation mechanism. The novel fusion of bilayer and floating mechanism is demonstrated by the bilayer floating drug delivery device. It demonstrates the effective creation of a controlled release Keywords: Fast releasing layer, sustained release layer, biphasic drug delivery, bilayer tablet. [Download Article] [Download Certifiate] |