REFERENCE VALUES FOR ELECTROLYTES, UREA AND CREATININE IN URINE OF YOUNG ADULTS SELECTED FROM THE UNIVERSITY OF BENIN CAMPUS AREA, NIGERIA
1Ugwu Juliana I*., 2Ugwu Okechukwu P.C., 1Olumese F.E., 2Enechi O.C. and 3Omeh Yusuf S.
1Department of Medical Biochemistry, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria.
2Department of Biochemistry,University of Nigeria, Nsukka, Enugu State, Nigeria.
3Department of Biochemistry, Michael Okpara, University of Agriculture, Umudike, Abia State, Nigeria.
ABSTRACT
This study was conducted to determine the reference values of urine
electrolytes, urea and creatinine in young adults. The study group
consisted of 17 males and 18 females aged (18-19) years, selected from
the University of Benin campus area. Sodium and potassium in urine
were measured by standard flame photometry, bicarbonate and
chloride levels were equally measured by simple titration methods,
creatinine level was analyzed by the Jaffe method and urea was
analyzed by the Berthelot reaction. The mean values in mmol/day for
both sexes are as follows: sodium: male-148.65±6.12, female-
127.89±4.48; potassium: male- 15.84±1.46, female- 11.28 ±1.43;
chloride: male - 111.29±8.24, female- 95.44±2.27; bicarbonate:male-
8.35±0.80, female- 7.83±0.56; urea: male- 433.12±56.16, female-323.33±51.64 and
creatinine: male- 33.54±56.16, female- 24.33±3.46. Significant differences were
observed in sodium and potassium levels in both sex groups (ρ0.05) when compared using
student’s t-test. Thus, these values are in agreement with previously suggested reference
ranges and could aid in health care management in the above population.
Keywords: Reference Value, Urea, Creatinine, Urine, Potassium.
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