Abstract

SIMULTANEOUS ESTIMATION OF ALOGLIPTIN BENZOATE AND PIOGLITAZONE HYDROCHLORIDE IN TABLET DOSAGE FORM USING UV-SPECTROSCOPY AND REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

Himani Gururani*, Ram Nivas, Monika Patel and Shamim Khan

ABSTRACT

Tablets are solid preparations that are nearly usually meant to be used orally, each containing a single dose of one or more active substances. They are made by compressing consistent quantities of particles. The most widely recommended dosage form is a tablet because it is a practical way to administer medication, has consistent dosage across tablets, is stable under a range of long-term storage conditions, and can be made using high-speed labeling, packing, and compression equipment. Because of this, advancements in tablet production technology are continuously being made to better their capacity to precisely administer a desired medicine in a dose form meant to have either immediate or long-term therapeutic effects.[1] The goal of standard compressed tablet modifications and technological advancements is to improve bioavailability and acceptance. In order toestablish a delivery method that is reasonably easy to administer, several sorts of newer, more efficient tablets are being developed. New methods of drug delivery have recently been developed as a result of certain technological advancements, including the ability to control the pace of drug delivery, sustain therapeutic activity for an extended period of time, and deliver drugs specifically to target tissues.[2]

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