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Citation | 5450 | 3969 |
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PHYTOTHERAPEUTIC APPROACHES FOR THE TREATMENT OF MULTIDRUG-RESISTANT TUBERCULOSIS: A COMPREHENSIVE REVIEW
Manjiri Jayawant*, Omkar Hulawale, Sahil Mishra, Avantika Bhanushali, Abhishek Dagade, Shivaji Giram and Priyanka Kalamkar
ABSTRACT
Multidrug-Resistant Tuberculosis (MDR-TB) poses a substantial global health threat, demanding novel strategies to combat its escalating prevalence and dire repercussions. The emergence of Mycobacterium tuberculosis strains resistant to conventional antibiotics has compelled the exploration of alternative therapeutic avenues. This review delves into the intricacies of MDR-TB and explores the potential of natural products as alternative anti- mycobacterial agents. MDR-TB, defined by resistance to isoniazid and rifampicin, presents a significant challenge, accounting for over 3% of newly reported TB cases globally. The incidence is markedly higher among individuals with previous TB treatment history. Conventional MDR-TB therapy entails extended regimens of second-line antibiotics, Keywords: Phytoconstituents, Natural products, MDR-TB, Antibiotic resistance. [Download Article] [Download Certifiate] |