Abstract

A REVIEW OF BOTULISM FROM DIFFERENT VIEWPOINTS

Mohd Tarif Ansari* and Anjali Singh

ABSTRACT

Botulism is commonly known as Clostridium Botulinum. The paralytic illness is brought on by the neurotoxin clostridium botulinum. This review provides a comprehensive overview of the disease, focusing on its laboratory diagnosis, and vaccination. Botulism is a disease that is both ancient and growing. The disease has caused life-threatening consequences for both humans and warm-blooded animals. The food-borne variety of botulism is the one with the most well-known usual clinical symptoms. Although uncommon, the sickness has the potential to be lethal and can masquerade as another condition, making diagnosis challenging. Both the diagnosis of botulism and the choice to administer a particular antidotal medication are primarily clinical. Botulism also affects the pregnancy period of women mainly in the third trimester and postpartum period. Despite being an effective strategy, vaccination against BONTs is still not recommended because of the increasing expectations regarding the therapeutic use of BONTs in a variety of clinical conditions A few variations in the treatment involve different methods of exposure, such as decontamination techniques, antidote administration and when necessary respiratory function support. Several terrorist groups and nations are believed to have or are experimenting with biological weapons programs. Botulism has been considered a biological warfare since IInd World War. One of the most significant role reversals of our day is the effective treatment of many neuromuscular disorders with botulism toxin, which is generally regarded as a terrible poison.

Keywords: Clostridium botulinum, Paralysis disease, Tetanus taxoid, Clostridium butyricum.