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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

INVESTIGATION OF AQUEOUS EXTRACT OF ROOTS OF CANTHIUM DICOCCUM IN STREPTOMYCIN INDUCED NEPHROTOXICITY IN ANIMAL MODEL

Malothu Nagulu*, T.Mangilal, R. Naga Kishore, G.Abhinayani and N.Sravya

ABSTRACT

The present study aimed to evaluate the protective effect of aqueous extract of canthium dicoccum against Streptomycin-induced nephrotoxocity in rats. Streptomycin -administered rats (control group) had encountered acute kidney dysfunction as evidenced by elevation in serum urea and creatinine. Treatment of aqueous extract of C.dicoccum at the dose level of 100 and 200mg/kg for 14 days significantly lowered the serum level of creatinine, urea and uric acid when compared with the control group. The statistical significance of the nephroprotective activity of C. dicoccum treated group and the Cystone treated group were compared against control were found almost equal as both groups gained significance (P

Keywords: Streptomycin, Canthium dicoccum, Cystone, Nephroprotective.

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