Abstract

PHYTOCONSTITUENTS AND DIVERSE PHARMACOLOGICAL POTENTIALS OF ADENIUM OBESUM: A CURRENT REVIEW

Robin Sharma*, Satyendra Kumar Rajput and Rohit Bhardwaj

ABSTRACT

Plants and their exudates have been steadily rising in traditional systems such as homoeopathy, acupuncture, aromatherapy, and the ayurvedic medicinal system since ancient times. Plants, in general, remain the best biological source of secondary metabolic chemicals that can be employed to treat a variety of ailments. The present study was designed on the phytoconstituents and diverse pharmacological potentials of Adenium obesum. Around 80% of people worldwide rely on herbal-based alternative medical systems like Ayurveda. The dogbane family includes the succulent plant Adenium obesum, sometimes known as desert rose. Apocyanacea is a native of Africa and can be found as a wild plant in Oman, Saudi Arabia, Yemen, Senegal, Somalia, and Ethiopia. All parts of a given species are used to treat a wide range of illnesses. Several plant species have been singled out for commercial cultivation due to their medicinal value. Carbohydrates, flavonoids, cardiac glycosides, flavonoids, terpenoids, and pregnanes were all identified in the selected plant during the phytochemical examination. The bulk of the isolated chemicals from the chosen plant had physiological effects. Previous studies of the selected plant have resulted in the extraction and identification of a total of 53 compounds. Stem and bark exhibited the chemical constituents as Betulin and Rosmarinic Acid. Stem showed 3,5,7,3,4,5-Hexahydroxy flavone and 5,7,3,4-Tetrahydroxy flavone whereas leaves confirmed for various chemical constituents i.e., Honghelin, Obeside-B & C. The plant demonstrated notable antibacterial, antioxidant, anti-cancer, antiplasmodial, anti-trypanosomal, and anti-leishmanial properties. It concludes that Adenium obesum has been utilized as pharmacological and ornamental plant worldwide. As its cultivation is quite feasible, it would be easily available and cost-effective in therapeutic uses.

Keywords: Herbal extract, Adenium obesum, Phytoconstituents, Pharmacological potentials.