![]() |
|||||||||||||
|
All | Since 2019 | |
Citation | 5450 | 3969 |
h-index | 23 | 20 |
i10-index | 134 | 84 |
EVALUATION OF ANTI-EPILEPTIC ACTIVITY OF HYDROALCOHOLIC EXTRACT OF Curcuma aromatica RHIZOME IN EXPERIMENTAL MICE
Suvarna Preetham K. P.*, Ashoka Shenoy M. and A. R. Shabaraya
ABSTRACT
Epilepsy is a disorder of the central nervous system and is characterized by periodic loss of consciousness with or without convulsions associated and with abnormal electrical activity in the brain. It is estimated that there are around 50 million people living with epilepsy globally. Around one-sixth of this population resides in India. A minority of patients may develop chronic epilepsy, and in such cases, treatment is more difficult. Hence there is a clear need to continue and identify novel AEDs that effectively control pharmaco-resistant seizure with minimal or no adverse effects. Plants may serve as the alternative sources for the development of new antiepileptic agents due to their biological activities. The rhizome of Curcuma aromatica used in traditional medicine to treat several pathologies like pains, fevers, bacterial infections, fungal infections. The current study was Keywords: Pentylenetetrazole; Curcuma aromatica; Convulsions; Phenytoin. [Download Article] [Download Certifiate] |