Abstract

ASSESSMENT OF ANTIBIOTIC SENSITIVITY PATTERN IN URINARY TRACT INFECTION IN A TERTIARY CARE TEACHING HOSPITAL

Bipin Shaji*, Chippymol Jopi and Shebi Babu

ABSTRACT

Introduction: Urinary tract infection is one of the most common urinary diseases that commonly occurs in females. In the majority of urinary tract infections, empirical antibiotic therapy is initiated before the culture sensitivity reports are made available, as it might be needed. Frequent changes in the antibiotics can increase the risk of antibiotic resistance. The objective of the study is to assess the antibiotic sensitivity pattern in urinary tract infections in a tertiary care teaching hospital. Methodology: The study is a prospective observational study conducted at the Department of Urology with 158 patients for a period of one year. The study included patients aged 18 years and above diagnosed with urinary tract infection. Pregnant and cancer patients were excluded from the study. The collected data were documented electronically using Microsoft Excel 2019 and statistically analyzed using descriptive statistics. Results: Among 158 patients, the majority of the patients were females with an age group between 60 and 69. The majority of the study population have diabetes mellitus and hypertension as the comorbid condition. In 158 urine samples, Escherichia coli was isolated from 62% (98 urine samples) of the samples, and it has the highest sensitivity towards linezolid, ceftriaxone, cefazolin, and nitrofurantoin followed by other penicillin and cephalosporin antibiotics. Conclusion: Escherichia coli is the most common uropathogen isolated and shows sensitivity towards linezolid, ceftriaxone, cefazolin, and nitrofurantoin, followed by other penicillin and cephalosporin antibiotics. Rational use of antibiotics must be ensured to provide quality care.

Keywords: Urinary tract infection, Antibiotics, Escherichia coli.