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SYNTHESIS, CHARACTERZATION AND BIOLOGICAL EVALUAVTION OF 2-(SUBSTITUTED THIAZOLIDINE -4-ONE)-1H -PHENYL BENZIMIDAZOLE
Kadapal Gopal*, D. Radha, Sidde Lahari, A. Ishwarya, E. Kavitha, K. Suchitra, K. Pavan Kumar and G. Maruthi Prasad
ABSTRACT
Benimidazole and its derivatives belong to a class of benzo-fused heterocyclic compounds. The presence of the thiazolidinone ring in a benzimidazole derivative enhances its pharmacological activity. Benimidazole derivatives have wide spectrum of biological activities like anti-hypertensive, anti-viral, anti-fungal, anti-tumor, analgesic and anthelmintic activity. A new series of 2-(substituted thiazolidine -4-one-1H-phenyl benzimidazole) were synthesized by three steps. Keywords: . [Download Article] [Download Certifiate] |