Abstract

IN-VITRO ANTIBACTERIAL ACTIVITY OF CNIDOSCOLUS CHAYAMANSA LEAVES EXTRACT ON SELECTIVE BACTERIAL STRAINS

Dr. Hannah Elizabeth S.*, Dr. Channamma G.M., Dr. D. Gnanasekaran, Dr. Reshma Karkera, Joel Durairaj G. and Dr. Shyam Kumar B.

ABSTRACT

Cnidoscolus chayamansa belongs to the family Euphorbiaceae and it is popular in Mexico and central America and now presently available in and around southern part of India. It possesses many uses antidiabetic, obesity, kidney stones, hemorrhoids, eye problems antimicrobial. The phytochemical prospection of dried leaves extracts showed the presence of different classes of secondary metabolites, as Saponins, Cardenolides, Flavonoids and Polyphenols that have demonstrated antimicrobial action. Fresh and dried leaves presented significantly antibacterial activity against all bacterial strains tested, specially Bacillus cereus MTCC 430, Staphylococcus aureus MTCC 2940, Escherichia coli MTCC 443 and Klebsiella pneumoniae MTCC 139. Ethanol and hexane extract fractions were effective against Escherichia coli and Bacillus cereus respectively.

Keywords: Cnidoscolus chayamansa, Bacterial Strains, Antibacterial, Agar well diffusion, Solvent extract, Ciprofloxacin.