Abstract

AN OVERVIEW OF MICRO EMULSION-BASED GELS

*Wagh S.V., Kamble A.R. and Hambare R.B.

ABSTRACT

Micro emulsions, Optically Isotropic and Thermodynamically Stable Systems of Water, Oil, Surfactants, and/or Cosurfactants, are Capable of Further Solubilizing and Sweetening Because of its current and general convenience, it is being investigated as a drug delivery system. A drug that is insoluble in water. It helps to solubilize the lipophilic part of the active ingredient and exhibits rapid and economical penetration into the skin. Therefore, it is useful for local drug delivery. For topical administration, microemulsions are incorporated into a composite gel base to extend the natural contact with the skin. Some widely used topical agents such as ointments, creams, and lotions have several drawbacks, including: B. The tackiness that causes discomfort to the patient after application has a Low spreading factor and thus has stability problems while rubbing and applying. Microemulsions have a stability disadvantage due to their low body, which is overcome by incorporating them into topical DDSs, which improves body, enables stratum corneum hydration, and increases a skin penetration of drugs. And increase skin flux. Owing to these factors, the use of transparent gels in Pharmaceutical formulations may become a major cluster for formulation.

Keywords: Microemulsion-Based Gels, Topical Drug delivery, Polymer.