SOLUBILITY ENHANCEMENT MEANING AND TECHNIQUES: A REVIEW
Laxmi Kanna*, Chaudhari Tamima, Payal Bijjargi and Tiwari Balkrishna
ABSTRACT
To improve the bioavailability and therapeutic efficacy of hydrophobic
medicines at the targeted area, the solubility enhancement technique is
essential in formulation development. About 40% of the new chemical
entities that have been identified by pharmaceutical industry screening
programs face numerous problems in the formulation and development
stage. The Bio pharmaceutics Classification System depicts that Class
II and IV drugs have a low water solubility, poor dissolution, and low
bioavailability.
Keywords: Solubility, need of solubility, BSCClassification, Factors Affecting Solubility of Solute in Liquids, Solubility Enhancement Techniques.
[Download Article]
[Download Certifiate]