Abstract

PHARMACOSOMES: THE FUTURE OF PRECISION DRUG RELEASE AND ENHANCED BIOAVALIBALITY

Y. Lalitha Laharika* and Dr. K.V. Ratnamala

ABSTRACT

Pharmacosomes are phospholipid-containing vesicular amphiphilic lipid structures that increase the bioavailability of insoluble medicines. Depending on the chemical makeup of the drug-lipid combination, they can exist as ultrafine vesicular, micellar, or hexagonal aggregates and are colloidal dispersions of medicines covalently bonded to lipids. The term "vesicular constructs" is used to describe pharmacosomes, liposomes, niosomes, and biosomes since these systems are created by joining a drug (pharmakon) to a carrier (soma). They are drugphospholipid complexes with active hydrogen that are Amphiphilic and bind to phospholipids. Pharmacosomes give the medicine greater biopharmaceutical qualities, which enhance bioavailability².The development of medication pharmacosomes has been demonstrated to increase absorption and reduce gastrointestinal toxicity. The majority of issues with liposomes, transferosomes, niosomes, and other similar structures can be solved with pharmacosomes. To achieve desired therapeutic objectives including drug targeting and controlled release, they are an effective tool.

Keywords: Pharmacosomes, Bioavailability, Preparation, Characterization &Application.