Abstract

A CONCISE REVIEW ON ANTIBACTERIAL ACTIVITY OF CURCUMIN AND AMLA

Deepanshu Pruthi, *Dr. Arun Kumar, Dr. Dinesh Kaushik and Devender Chauhan

ABSTRACT

Herbal drugs constitute traditional medicines which primarily use medicinal plant preparations for therapy. Allopathic medicine system and modern medicine system has gained popularity due to more and more scientific discoveries and advancement in modern scientific research .Herbal medicine was also an effective healing method and more therapeutic. The maceration is a method of solid–liquid extraction. Bioactive compounds in plants include alkaloids, terpenoids, coumarins, flavonoids, nitrogen-containing compounds, organosulfur compounds, phenolics, etc. A wide spectrum of bioactivities is exhibited by these compounds such as anti-inflammatory, immunostimulatory, anticancer, antioxidant, antimicrobial, etc. Curcuma longa is a perennial herb and family is Zingiberaceae. Ayurvedic systems of medicine, particularly as an anti-inflammatory agent, and for the treatment of flatulence, jaundice, menstrual difficulties, hematuria, hemorrhage, and colic. Emblica, Indian goose berry (amla) the fruit that contains considerably higher concentration of most minerals and amino acids. The pulpy portion of fruit, dried and freed from the nuts contains: gallic acid 1.32%, tannin, sugar 36.10%; gum 13.75%; albumin 13.08%; crude cellulose 17.08%; mineral matter 4.12%; and moisture 3.83%. Tannins are the mixture of gallic acid, ellagic acid, and phyllembin. Lotions are defined as monophasic or biphasic solution, emulsion or suspension design to apply on unbroken and also broken or inflamed skin without friction. Antimicrobial agents are essentially important in reducing the global burden of infectious diseases. However, emergence and dissemination of multidrug resistant (MDR) strain in pathogenic bacteria have become a significant public health threat as there are fewer, or even sometimes no, effective antimicrobial agents available for the infection caused by pathogenic bacteria. Many plants have been used because of their antimicrobial traits, which are due to phytochemicals synthesized in the secondary metabolism of the plant. Plants are rich in a wide variety of secondary metabolites such as tannins, alkaloids, phenolic compounds, and flavonoids, which have been found in vitro to have antimicrobial properties.

Keywords: Herbal medicine, Alkaloids, Microbial Activity, Anti-inflammatory.