Abstract

NEPHROPROTECTIVE ROLE OF ADHUSADI KWATH AND CHANDRAPRABHA VATI IN MICROALBUMINURIA ASSOCIATED TO TYPE 2 DIABETES MELLITUS - A CASE REPORT

Jupitora Dutta* and Om Prakash Gupta

ABSTRACT

Type2 Diabetes mellitus is a public health concern, and projections of its future effects are alarming. Diabetic Nephropathy (DN) is a common finding in diabetic patients. Microalbuminuria is the earliest clinical evidence of DN. Diabetes Mellitus (DM) is one among the most common lifestyle related disorders in the present era. In type II DM, prevalence of microalbuminuria is 20-25% in both newly diagnosed and established cases. Microalbuminuria defined as urinary albumin excretion of 30–300 mg/day is an earlier sign of vascular damage due to complications of DM and a marker of general vascular dysfunction. Microalbuminuria is seen in the third stage of diabetic nephropathy and is a leading cause of End Stage Renal Disorder (ESRD). In Ayurveda, Lakshanas (symptoms) of Kaphapittavruta Madhumeha (DM with Kapha and Pitta obstruction) show similarity to the features of microalbuminuria Early detection of Microalbuminuria is very important, it allows timely interventions to prevent progression to macro albuminuria and later end stage renal disease. In Ayurveda Diabetic Nephropathy can be considered as a complication of Madhumeha and proper management of Madhumeha will prevent the progression of the disease. 65 year old female patient, who is a known case of Type 2 DM since 10 years, came to Govt. Ayurvedic College and Hospital, Jalukbari, Assam Kayachikitsa OPD with complaints of frothy urine and bilateral ankle swelling since 6 months. Screening for Microalbuminuria was done in a 24-hour urine sample and was found to be 332 mg/dl. The patient was recommended to take Chandraprabha vati 1 tab thrice daily and Adhusa, Hariraki, Chitrak, Saptaparna kwath 20 ml twice daily. After the prescribed study period, subjective and objective criteria were recorded and showed significant results.

Keywords: Microalbuminuria, Madhumeha.