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EVALUATION OF ANTIMICROBIAL AND ANTIBIOFILM POTENTIAL OF ALUM (SPHATIKA) AND IT’S BHASMA (SPHATIKA BHASMA) AGAINST CLINICAL ISOLATES- AN IN VITRO STUDY
Dr. Anuya Aparna Rege*, Mrs. Dipti Bhushan Kolte, Ms. Mrudali Sanjay Ambre
ABSTRACT
Natural products have played a key role in drug discovery especially against infectious diseases. One such natural products used for therapeutic purposes is Alum (Sphatika). Besides, Ayurvedic “Bhasma” formulations have been used for treatment of various ailments widely in India. Hence, in the present in vitro study, antimicrobial activities of Alum (Sphatika) and Sphatika Bhasma were evaluated against total 6 clinical isolates, viz., K. aerogenes, K. pneumoniae, P. aeruginosa, P. mirabilis, P. vulgaris, S. flexneri and a mixed culture, using various assays such as MIC, MBC and Agar Well Diffusion Method. Further, their effect on bacterial biofilms was also detected using crystal violet staining method. The antibiofilm activity Keywords: Alum, Sphatika Bhasma, Ayurveda, Natural Products, Antimicrobial, Antibiofilm. [Download Article] [Download Certifiate] |