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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

DEVELOPMENT AND VALIDATION OF SIMPLE UV SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF CYCLOBENZAPRINE BOTH IN BULK & IN MARKETED DOSAGE FORMULATION

Chetna Ramchandra Madke*, Hitesh Motilal Jain,Minal T. Harde,Pravin D. Chaudhari

ABSTRACT

A rapid, simple & economic UV spectrophotometric method was developed & validated for estimation of cyclobenzaprine hydrochloride in bulk & pharmaceutical dosage formulation. At the predetermined absorbance maxima of 290nm, the calibration curve linear in the range of 4-24 μg/ml & has correlation coefficient R2=0.999 & good mean recovery (99.04-100.89 %). The method is developed using methanol &water as a solvent & results were validated as per ICH guidelines for Accuracy, precision, linearity, LOD, LOQ & found to be satisfactory.

Keywords: Cyclobenzaprine hydrochloride, UV spectrophotometry, Validation

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