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Abstract

BERBERINE: A POTENTIAL THERAPEUTIC CANDIDATE FOR BREAST CANCER

A.B.M. Anwarul Bashar, Md. Shahadat Hossan, Rownak Jahan, Abdullah Al-Nahain, A.K.M. Mahmudul Haque, Mohammed Rahmatullah*

ABSTRACT

Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids, and which can be found mostly in plant species belonging to the Berberis genus. Recent studies have demonstrated numerous pharmacological properties of the compound, among which the most pronounced being anticancer effects against a wide variety of cancer cell lines. In this review, we discuss the anticancer effects of berberine against breast cancer and its potential for therapeutic applications.

Keywords: Berberine, anticancer, Berberidaceae, breast cancer.


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