Abstract

REVIEW ON BILAYER TABLET

Ashwini Bramahanand Dupargude*, Dr. Rajendra Patil and Dr. K.R. khandelwal

ABSTRACT

Bilayer tablet is the novel technology for the development of controlled release formulation. Developing a combination of two or more active pharmaceutical ingredients in a single dosage form is known as a bilayer tablet. Now a days the use of bilayer tablets has been increased. Bilayer tablet is more suitable for gradual release of two active ingredients in combination. Bilayer tablet technology helps in separating the two incompatible substances in which one layer is immediate release as loading dose and second layer is controlled/sustained release as maintenance dose. Two incompatible drugs can also be formulated into a bilayer tablet by adding an inert intermediate layer.

Keywords: Bilayer tablet, Formulation, Controlled release, Tablet press.