Abstract

EXTRACTION AND EVALUATION OF ANTHELMINTIC ACTIVITY USING NYCTANTHES ARBOR-TRISTIS LINN AND MOMORDICA CHARANTIA

Bongirwar Nidhi*, Male Prashanth Goud, Ratlavath Lokiya Nayak, G. Lalitha Hiranmai, E. Uday Kumar and Dr. Chandrasekhara Rao Baru

ABSTRACT

Alcoholic extract (Ethanol) from the fruits and flowers of Momordica charantia and nyctanthes arbor tristis respectively was extracted using Soxhlet apparatus and were investigated for their combined anthelmintic activity against Pheretima posthuma. Five different concentrations (25, 50,100,150,200 and 250 mg/ml) of the extract were studied in activity, which involved the determination of time of paralysis and time of death of the worm. The combined extracts exhibited significant anthelmintic activity at highest concentration of 250 mg/ml. albendazole in same concentration as that of extract was included as standard reference and distilled water as control. The anthelmintic activity of combined ethanolic extracts of Momordica charantia and nyctanthes arbor tristis has therefore been demonstrated for the first time.

Keywords: Alcoholic extract (Ethanol) from the fruits and flowers of Momordica charantia and nyctanthes arbor tristis respectively was extracted using Soxhlet apparatus and were investigated for their combined anthelmintic activity against Pheretima posthuma. Five